Chloroquine neither eliminates liver stage parasites nor delays their development in a murine Chemoprophylaxis Vaccination model

Chemoprophylaxis Vaccination (CVac) confers long lasting sterile protection against homologous parasite strains in humans, and involves inoculation of infectious sporozoites (SPZ) under drug cover. CVac using the drug chloroquine (CQ) induces pre-erythrocytic immunity in humans that includes antibod...

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Bibliografische gegevens
Gepubliceerd in:Front Microbiol
Hoofdauteurs: Sahu, Tejram, Lambert, Lynn, Herrod, Jessica, Conteh, Solomon, Orr-Gonzalez, Sachy, Carter, Dariyen, Duffy, Patrick E.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2015
Onderwerpen:
Microbiology
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4391028/
https://ncbi.nlm.nih.gov/pubmed/25914686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2015.00283
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