End-Product Diacylglycerol Enhances the Activity of PI-PLC through Changes in Membrane Domain Structure

Diacylglycerol (DAG)-induced activation of phosphatidylinositol-phospholipase C (PI-PLC) was studied with vesicles containing PI, either pure or in mixtures with dimyristoyl phosphatidylcholine, distearoyl phosphatidylcholine, sphingomyelin, or galactosylceramide, used as substrates. At 22°C, DAG at...

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Detalles Bibliográficos
Publicado en:Biophys J
Main Authors: Ahyayauch, Hasna, Sot, Jesús, Collado, M. Isabel, Huarte, Nerea, Requejo-Isidro, José, Alonso, Alicia, Goñi, Félix M.
Formato: Artigo
Idioma:Inglês
Publicado: The Biophysical Society 2015
Assuntos:
Membranes
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4390822/
https://ncbi.nlm.nih.gov/pubmed/25863059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2015.02.020
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