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Synthesis, Antitumor Activity, and Mechanism of Action of 6-Acrylic Phenethyl Ester-2-pyranone Derivatives

Based on the scaffolds of caffeic acid phenethyl ester (CAPE) as well as bioactive lactone-containing compounds, 6-acrylic phenethyl ester-2-pyranone derivatives were synthesized and evaluated against five tumor cell lines (HeLa, C6, MCF-7, A549, and HSC-2). Most of the new derivatives exhibited mod...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Org Biomol Chem
Hauptverfasser: Fang, Sai, Chen, Lei, Yu, Miao, Cheng, Bao, Lin, Yongsheng, Morris-Natschke, Susan L., Lee, Kuo-Hsiung, Gu, Qiong, Xu, Jun
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4390547/
https://ncbi.nlm.nih.gov/pubmed/25800703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5ob00007f
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