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AUF-1 and YB-1 independently regulate β-globin mRNA in developing erythroid cells through interactions with poly(A)-binding protein

The normal expression of β-globin protein in mature erythrocytes is critically dependent on post-transcriptional events in erythroid progenitors that ensure the high stability of β-globin mRNA. Previous work has revealed that these regulatory processes require AUF-1 and YB-1, two RNA-binding protein...

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Detalhes bibliográficos
Publicado no:Mech Dev
Main Authors: van Zalen, Sebastiaan, Lombardi, Alyssa A., Jeschke, Grace R., Hexner, Elizabeth O., Russell, J. Eric
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4390516/
https://ncbi.nlm.nih.gov/pubmed/25720531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mod.2015.02.003
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