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Galectin-3 shapes antitumor immune responses by suppressing CD8(+) T cells via LAG-3 and inhibiting expansion of plasmacytoid dendritic cells
Galectin-3 is a 31 kD lectin that modulates T-cell responses through several mechanisms including apoptosis, T-cell receptor (TCR) cross-linking, and TCR down-regulation. We found patients with pancreatic ductal adenocarcinoma (PDA) responding to a granulocyte-macrophage colony-stimulating factor (G...
Tallennettuna:
| Julkaisussa: | Cancer Immunol Res |
|---|---|
| Päätekijät: | , , , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2015
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4390508/ https://ncbi.nlm.nih.gov/pubmed/25691328 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-14-0150 |
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