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Fasciola hepatica fatty acid binding protein inhibits TLR4 activation and suppresses the inflammatory cytokines induced by LPS in vitro and in vivo

Toll-like receptor 4 (TLR4), the innate immunity receptor for bacterial endotoxins, plays a pivotal role in the induction of inflammatory responses. There is a need to develop molecules that block either activation through TLR4 or the downstream signaling pathways to inhibit the storm of inflammatio...

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Pubblicato in:J Immunol
Autori principali: Martin, Ivelisse, Cabán-Hernández, Kimberly, Figueroa-Santiago, Olgary, Espino, Ana M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4390499/
https://ncbi.nlm.nih.gov/pubmed/25780044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1401182
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