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Interleukin-12 promotes myeloid-derived suppressor cell (MDSC) recruitment and bacterial persistence during S. aureus orthopedic implant infection
Staphylococcus aureus (S. aureus) is a leading cause of human prosthetic joint infections (PJIs) typified by biofilm formation. We recently identified a critical role for myeloid-derived suppressor cells (MDSCs) in S. aureus biofilm persistence. Pro-inflammatory signals induce MDSC recruitment and a...
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| Publicado no: | J Immunol |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4390492/ https://ncbi.nlm.nih.gov/pubmed/25762781 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1402689 |
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