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Genetic evidence that intratumoral T-cell proliferation and activation is associated with recurrence and survival in patients with resected colorectal liver metastases

Though immune responses correlate with prognosis in primary colorectal cancer, the role of tumor immunity in metastatic disease is less clear. We hypothesized that patient survival and tumor recurrence correlate with transcriptional evidence of lymphocyte proliferation/activation in resected colorec...

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Detalhes bibliográficos
Publicado no:Cancer Immunol Res
Main Authors: Maker, Ajay V., Ito, Hiromichi, Mo, Qianxing, Weisenberg, Elliot, Qin, Li-Xuan, Turcotte, Simon, Maithel, Shishir, Shia, Jinru, Blumgart, Leslie, Fong, Yuman, Jarnagin, William R., DeMatteo, Ronald P., D'Angelica, Michael I.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4390462/
https://ncbi.nlm.nih.gov/pubmed/25600439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-14-0212
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