Botulinum Neurotoxin Type A Induces TLR2-Mediated Inflammatory Responses in Macrophages

Botulinum neurotoxin type A (BoNT/A) is the most potent protein toxin and causes fatal flaccid muscle paralysis by blocking neurotransmission. Application of BoNT/A has been extended to the fields of therapeutics and biodefense. Nevertheless, the global response of host immune cells to authentic BoN...

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Vydáno v:PLoS One
Hlavní autoři: Kim, Yun Jeong, Kim, Jeong-Hee, Lee, Kwang-Jun, Choi, Myung-Min, Kim, Yeon Hee, Rhie, Gi-eun, Yoo, Cheon-Kwon, Cha, Kiweon, Shin, Na-Ri
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2015
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4390353/
https://ncbi.nlm.nih.gov/pubmed/25853816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0120840
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