Impact of the CFTR-Potentiator Ivacaftor on Airway Microbiota in Cystic Fibrosis Patients Carrying A G551D Mutation

BACKGROUND: Airway microbiota composition has been clearly correlated with many pulmonary diseases, and notably with cystic fibrosis (CF), an autosomal genetic disorder caused by mutation in the CF transmembrane conductance regulator (CFTR). Recently, a new molecule, ivacaftor, has been shown to re-...

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Udgivet i:PLoS One
Main Authors: Bernarde, Cédric, Keravec, Marlène, Mounier, Jérôme, Gouriou, Stéphanie, Rault, Gilles, Férec, Claude, Barbier, Georges, Héry-Arnaud, Geneviève
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4390299/
https://ncbi.nlm.nih.gov/pubmed/25853698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0124124
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