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Quantitative Protein Topography Analysis and High-Resolution Structure Prediction Using Hydroxyl Radical Labeling and Tandem-Ion Mass Spectrometry (MS)

Hydroxyl radical footprinting based MS for protein structure assessment has the goal of understanding ligand induced conformational changes and macromolecular interactions, for example, protein tertiary and quaternary structure, but the structural resolution provided by typical peptide-level quantif...

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Detalles Bibliográficos
Publicado en:Mol Cell Proteomics
Main Authors: Kaur, Parminder, Kiselar, Janna, Yang, Sichun, Chance, Mark R.
Formato: Artigo
Idioma:Inglês
Publicado: The American Society for Biochemistry and Molecular Biology 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4390260/
https://ncbi.nlm.nih.gov/pubmed/25687570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.O114.044362
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