Dose-Dependent ATP Depletion and Cancer Cell Death following Calcium Electroporation, Relative Effect of Calcium Concentration and Electric Field Strength

BACKGROUND: Electroporation, a method for increasing the permeability of membranes to ions and small molecules, is used in the clinic with chemotherapeutic drugs for cancer treatment (electrochemotherapy). Electroporation with calcium causes ATP (adenosine triphosphate) depletion and cancer cell dea...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Hansen, Emilie Louise, Sozer, Esin Bengisu, Romeo, Stefania, Frandsen, Stine Krog, Vernier, P. Thomas, Gehl, Julie
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4390219/
https://ncbi.nlm.nih.gov/pubmed/25853661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0122973
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