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Cerebrospinal Fluid Cytokine Profiles Predict Risk of Early Mortality and Immune Reconstitution Inflammatory Syndrome in HIV-Associated Cryptococcal Meningitis

Understanding the host immune response during cryptococcal meningitis (CM) is of critical importance for the development of immunomodulatory therapies. We profiled the cerebrospinal fluid (CSF) immune-response in ninety patients with HIV-associated CM, and examined associations between immune phenot...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Jarvis, Joseph N., Meintjes, Graeme, Bicanic, Tihana, Buffa, Viviana, Hogan, Louise, Mo, Stephanie, Tomlinson, Gillian, Kropf, Pascale, Noursadeghi, Mahdad, Harrison, Thomas S.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4390200/
https://ncbi.nlm.nih.gov/pubmed/25853653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004754
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