Human Embryonic Stem Cells Form Functional Thyroid Follicles

Objective: The molecular events that lead to human thyroid cell speciation remain incompletely characterized. It has been shown that overexpression of the regulatory transcription factors Pax8 and Nkx2-1 (ttf-1) directs murine embryonic stem (mES) cells to differentiate into thyroid follicular cells...

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Bibliographic Details
Published in:Thyroid
Main Authors: Ma, Risheng, Latif, Rauf, Davies, Terry F.
Format: Artigo
Language:Inglês
Published: Mary Ann Liebert, Inc. 2015
Subjects:
Thyroid Economy: Regulation, Cell Biology, and Thyroid Hormone Metabolism and Action
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4390159/
https://ncbi.nlm.nih.gov/pubmed/25585054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/thy.2014.0537
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