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Disease-Promoting Effects of Type I Interferons in Viral, Bacterial, and Coinfections

While type I interferons (IFNs) are universally acknowledged for their antiviral and immunostimulatory functions, there is increasing appreciation of the detrimental effects of inappropriate, excessive, or mistimed type I IFN responses in viral and bacterial infections. The underlying mechanisms by...

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Pubblicato in:J Interferon Cytokine Res
Autori principali: Davidson, Sophia, Maini, Mala K., Wack, Andreas
Natura: Artigo
Lingua:Inglês
Pubblicazione: Mary Ann Liebert, Inc. 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4389918/
https://ncbi.nlm.nih.gov/pubmed/25714109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/jir.2014.0227
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