Mesenchymal stem cells enhance autophagy and increase β-amyloid clearance in Alzheimer disease models

Current evidence suggests a central role for autophagy in Alzheimer disease (AD), and dysfunction in the autophagic system may lead to amyloid-β (Aβ) accumulation. Using in vitro and in vivo AD models, the present study investigated whether mesenchymal stem cells (MSCs) could enhance autophagy and t...

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Detalhes bibliográficos
Publicado no:Autophagy
Main Authors: Shin, Jin Young, Park, Hyun Jung, Kim, Ha Na, Oh, Se Hee, Bae, Jae-Sung, Ha, Hee-Jin, Lee, Phil Hyu
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2014
Assuntos:
Basic Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4389879/
https://ncbi.nlm.nih.gov/pubmed/24149893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.26508
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