Toward the Establishment of Standardized In Vitro Tests for Lipid-Based Formulations, Part 6: Effects of Varying Pancreatin and Calcium Levels

The impact of pancreatin and calcium addition on a wide array of lipid-based formulations (LBFs) during in vitro lipolysis, with regard to digestion rates and distribution of the model drug danazol, was investigated. Pancreatin primarily affected the extent of digestion, leaving drug distribution so...

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Detalhes bibliográficos
Publicado no:AAPS J
Main Authors: Sassene, Philip, Kleberg, Karen, Williams, Hywel D., Bakala-N’Goma, Jean-Claude, Carrière, Frédéric, Calderone, Marilyn, Jannin, Vincent, Igonin, Annabel, Partheil, Anette, Marchaud, Delphine, Jule, Eduardo, Vertommen, Jan, Maio, Mario, Blundell, Ross, Benameur, Hassan, Porter, Christopher J. H., Pouton, Colin W., Müllertz, Anette
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4389749/
https://ncbi.nlm.nih.gov/pubmed/25274609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-014-9672-x
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