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Heteroduplex rejection during single-strand annealing requires Sgs1 helicase and mismatch repair proteins Msh2 and Msh6 but not Pms1

Recombination between moderately divergent DNA sequences is impaired compared with identical sequences. In yeast, an HO endonuclease-induced double-strand break can be repaired by single-strand annealing (SSA) between flanking homologous sequences. A 3% sequence divergence between 205-bp sequences f...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Sugawara, Neal, Goldfarb, Tamara, Studamire, Barbara, Alani, Eric, Haber, James E.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2004
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC438974/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15199178/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0305749101
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