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Prediction of Drug Clearance in Children: an Evaluation of the Predictive Performance of Several Models
The objective of this study is to evaluate the predictive performance of several models to predict drug clearance in children ≤5 years of age. Six models (allometric model (data-dependent exponent), fixed exponent of 0.75 model, maturation model, body weight-dependent model, segmented allometric mod...
Tallennettuna:
| Julkaisussa: | AAPS J |
|---|---|
| Päätekijät: | , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Springer US
2014
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4389735/ https://ncbi.nlm.nih.gov/pubmed/25274608 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-014-9667-7 |
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