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Direct imaging shows that insulin granule exocytosis occurs by complete vesicle fusion
Confocal imaging of GFP-tagged secretory granules combined with the use of impermeant extracellular dyes permits direct observation of insulin packaged in secretory granules, trafficking of these granules to the plasma membrane, exocytotic fusion of granules with the plasma membrane, and eventually...
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| Autori principali: | , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2004
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC438965/ https://ncbi.nlm.nih.gov/pubmed/15197259 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0403201101 |
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