Molecular mechanisms of NET formation and degradation revealed by intravital imaging in the liver vasculature

Neutrophil extracellular traps (NETs) composed of DNA decorated with histones and proteases trap and kill bacteria but also injure host tissue. Here we show that during a bloodstream infection with methicillin-resistant Staphylococcus aureus, the majority of bacteria are sequestered immediately by h...

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Bibliographic Details
Published in:Nat Commun
Main Authors: Kolaczkowska, Elzbieta, Jenne, Craig N., Surewaard, Bas G. J., Thanabalasuriar, Ajitha, Lee, Woo-Yong, Sanz, Maria-Jesus, Mowen, Kerri, Opdenakker, Ghislain, Kubes, Paul
Format: Artigo
Language:Inglês
Published: Nature Pub. Group 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4389265/
https://ncbi.nlm.nih.gov/pubmed/25809117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms7673
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