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Accuracy of receptor-based methods for detection of thyrotropin-receptor autoantibodies: a new automated third-generation immunoassay shows higher analytical and clinical sensitivity for the differential diagnosis of hyperthyroidism

PURPOSE: Specific autoantibodies acting as TSH receptor agonists (TRAb) are responsible for Graves’ disease (GD). In the last 30 years three generations of assay methods for the detection of TRAb have become available. The aim of this multicentre study was to evaluate the analytical sensitivity, pre...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Auto Immun Highlights
Hauptverfasser: Tozzoli, Renato, Kodermaz, Graziano, Villalta, Danilo, Bagnasco, Marcello, Pesce, Giampaola, Bizzaro, Nicola
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer International Publishing 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4389045/
https://ncbi.nlm.nih.gov/pubmed/26000113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13317-010-0014-4
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