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DSCAM Promotes Refinement in the Mouse Retina through Cell Death and Restriction of Exploring Dendrites
In this study we develop and use a gain-of-function mouse allele of the Down syndrome cell adhesion molecule (Dscam) to complement loss-of-function models. We assay the role of Dscam in promoting cell death, spacing, and laminar targeting of neurons in the developing mouse retina. We find that ectop...
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| Vydáno v: | J Neurosci |
|---|---|
| Hlavní autoři: | , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Society for Neuroscience
2015
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4388924/ https://ncbi.nlm.nih.gov/pubmed/25855178 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2202-14.2015 |
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