Radiological and Pathological Features Associated with IDH1-R132H Mutation Status and Early Mortality in Newly Diagnosed Anaplastic Astrocytic Tumours

BACKGROUND: Glioblastoma can occur either de novo or by the transformation of a low grade tumour; the majority of which harbor a mutation in isocitrate dehydrogenase (IDH1). Anaplastic tumours are high-grade gliomas that may represent the final step in the evolution of a secondary glioblastoma or th...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Wasserman, Jason K., Nicholas, Garth, Yaworski, Rebecca, Wasserman, Anne-Marie, Woulfe, John M., Jansen, Gerard H., Chakraborty, Santanu, Nguyen, Thanh B.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4388816/
https://ncbi.nlm.nih.gov/pubmed/25849605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0123890
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