G-CSF Protects Human Brain Vascular Endothelial Cells Injury Induced by High Glucose, Free Fatty Acids and Hypoxia through MAPK and Akt Signaling

Granulocyte-colony stimulating factor (G-CSF) has been shown to play a neuroprotective role in ischemic stroke by mobilizing bone marrow (BM)-derived endothelial progenitor cells (EPCs), promoting angiogenesis, and inhibiting apoptosis. Impairments in mobilization and function of the BM-derived EPCs...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Su, Jingjing, Zhou, Houguang, Tao, Yinghong, Guo, Jingchun, Guo, Zhuangli, Zhang, Shuo, Zhang, Yu, Huang, Yanyan, Tang, Yuping, Dong, Qiang, Hu, Renming
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4388714/
https://ncbi.nlm.nih.gov/pubmed/25849550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0120707
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