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Uniform Sampling of Steady States in Metabolic Networks: Heterogeneous Scales and Rounding

The uniform sampling of convex polytopes is an interesting computational problem with many applications in inference from linear constraints, but the performances of sampling algorithms can be affected by ill-conditioning. This is the case of inferring the feasible steady states in models of metabol...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: De Martino, Daniele, Mori, Matteo, Parisi, Valerio
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4388631/
https://ncbi.nlm.nih.gov/pubmed/25849140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0122670
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