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IL-21R Signaling Suppresses IL-17(+) Gamma Delta T Cell Responses and Production of IL-17 Related Cytokines in the Lung at Steady State and After Influenza A Virus Infection

Influenza A virus (IAV) infection of the respiratory tract elicits a robust immune response, which is required for efficient virus clearance but at the same time can contribute to lung damage and enhanced morbidity. IL-21 is a member of the type I cytokine family and has many different immune-modula...

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Pubblicato in:PLoS One
Autori principali: Moser, Emily K., Sun, Jie, Kim, Taeg S., Braciale, Thomas J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4388622/
https://ncbi.nlm.nih.gov/pubmed/25849970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0120169
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