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Simultaneous Discovery, Estimation and Prediction Analysis of Complex Traits Using a Bayesian Mixture Model

Gene discovery, estimation of heritability captured by SNP arrays, inference on genetic architecture and prediction analyses of complex traits are usually performed using different statistical models and methods, leading to inefficiency and loss of power. Here we use a Bayesian mixture model that si...

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Vydáno v:PLoS Genet
Hlavní autoři: Moser, Gerhard, Lee, Sang Hong, Hayes, Ben J., Goddard, Michael E., Wray, Naomi R., Visscher, Peter M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4388571/
https://ncbi.nlm.nih.gov/pubmed/25849665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004969
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