Deep Sequencing of the Trypanosoma cruzi GP63 Surface Proteases Reveals Diversity and Diversifying Selection among Chronic and Congenital Chagas Disease Patients

BACKGROUND: Chagas disease results from infection with the diploid protozoan parasite Trypanosoma cruzi. T. cruzi is highly genetically diverse, and multiclonal infections in individual hosts are common, but little studied. In this study, we explore T. cruzi infection multiclonality in the context o...

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發表在:PLoS Negl Trop Dis
Main Authors: Llewellyn, Martin S., Messenger, Louisa A., Luquetti, Alejandro O., Garcia, Lineth, Torrico, Faustino, Tavares, Suelene B. N., Cheaib, Bachar, Derome, Nicolas, Delepine, Marc, Baulard, Céline, Deleuze, Jean-Francois, Sauer, Sascha, Miles, Michael A.
格式: Artigo
語言:Inglês
出版: Public Library of Science 2015
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4388557/
https://ncbi.nlm.nih.gov/pubmed/25849488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0003458
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