Combination of X-ray crystallography, SAXS and DEER to obtain the structure of the FnIII-3,4 domains of integrin α6β4

Integrin α6β4 is a major component of hemidesmosomes that mediate the stable anchorage of epithelial cells to the underlying basement membrane. Integrin α6β4 has also been implicated in cell proliferation and migration and in carcinoma progression. The third and fourth fibronectin type III domains (...

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Detalhes bibliográficos
Publicado no:Acta Crystallogr D Biol Crystallogr
Main Authors: Alonso-García, Noelia, García-Rubio, Inés, Manso, José A., Buey, Rubén M., Urien, Hector, Sonnenberg, Arnoud, Jeschke, Gunnar, de Pereda, José M.
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2015
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4388270/
https://ncbi.nlm.nih.gov/pubmed/25849406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1399004715002485
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