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The architecture of amyloid-like peptide fibrils revealed by X-ray scattering, diffraction and electron microscopy
Structural analysis of protein fibrillation is inherently challenging. Given the crucial role of fibrils in amyloid diseases, method advancement is urgently needed. A hybrid modelling approach is presented enabling detailed analysis of a highly ordered and hierarchically organized fibril of the GNNQ...
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| Publié dans: | Acta Crystallogr D Biol Crystallogr |
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| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
International Union of Crystallography
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4388266/ https://ncbi.nlm.nih.gov/pubmed/25849399 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1399004715001674 |
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