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Binge-Like Consumption of Ethanol and Other Salient Reinforcers is Blocked by Orexin-1 Receptor Inhibition and Leads to a Reduction of Hypothalamic Orexin Immunoreactivity

BACKGROUND: Orexin (OX) neurons originating in the lateral hypothalamus (LH) are ideally positioned to modulate reward processing as they form connections with several key brain regions known to be involved in the reward pathway. Consistent with these findings, a growing number of studies have impli...

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Bibliographic Details
Published in:Alcohol Clin Exp Res
Main Authors: Olney, Jeffrey J., Navarro, Montserrat, Thiele, Todd E.
Format: Artigo
Language:Inglês
Published: 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4387868/
https://ncbi.nlm.nih.gov/pubmed/25623402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acer.12591
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