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SMARCE1 suppresses EGFR expression and controls responses to MET and ALK inhibitors in lung cancer
Recurrent inactivating mutations in components of SWI/SNF chromatin-remodeling complexes have been identified across cancer types, supporting their roles as tumor suppressors in modulating oncogenic signaling pathways. We report here that SMARCE1 loss induces EGFR expression and confers resistance t...
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| Publicat a: | Cell Res |
|---|---|
| Autors principals: | , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4387553/ https://ncbi.nlm.nih.gov/pubmed/25656847 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2015.16 |
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