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Chronic nicotine treatment enhances vascular smooth muscle relaxation in rats

AIM: To investigate the effect of chronic nicotine treatment on vascular function and to identify the underlying mechanisms. METHODS: Adult rats were treated with nicotine (3 mg·kg(−1)·d(−1), sc) for 6 weeks. After the rats were sacrificed, aortic rings were prepared for detecting vascular reactivit...

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Опубликовано в: :Acta Pharmacol Sin
Главные авторы: Xu, Tian-ying, Lan, Xiao-hong, Guan, Yun-feng, Zhang, Sai-long, Wang, Xia, Miao, Chao-yu
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2015
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4387309/
https://ncbi.nlm.nih.gov/pubmed/25832423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2015.5
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