Hematopoietic stem cell quiescence and function are controlled by the CYLD–TRAF2–p38MAPK pathway

The status of long-term quiescence and dormancy guarantees the integrity of hematopoietic stem cells (HSCs) during adult homeostasis. However the molecular mechanisms regulating HSC dormancy remain poorly understood. Here we show that cylindromatosis (CYLD), a tumor suppressor gene and negative regu...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Exp Med
Egile Nagusiak: Tesio, Melania, Tang, Yilang, Müdder, Katja, Saini, Massimo, von Paleske, Lisa, Macintyre, Elizabeth, Pasparakis, Manolis, Waisman, Ari, Trumpp, Andreas
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The Rockefeller University Press 2015
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4387289/
https://ncbi.nlm.nih.gov/pubmed/25824820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20141438
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