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Hematopoietic stem cell quiescence and function are controlled by the CYLD–TRAF2–p38MAPK pathway
The status of long-term quiescence and dormancy guarantees the integrity of hematopoietic stem cells (HSCs) during adult homeostasis. However the molecular mechanisms regulating HSC dormancy remain poorly understood. Here we show that cylindromatosis (CYLD), a tumor suppressor gene and negative regu...
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| Publicado no: | J Exp Med |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4387289/ https://ncbi.nlm.nih.gov/pubmed/25824820 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20141438 |
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