In Vitro Analysis of Transport and Metabolism of 4'-Thiothymidine in Human Tumor Cells

INTRODUCTION: The use of thymidine (TdR) and thymidine analogs such as 3′-fluoro-3′-deoxythymidine (FLT) as positron emission tomography (PET)-based proliferation markers can provide information on tumor response to treatment. Studies on another TdR analog, 4'-thiothymidine (4DST), suggest that...

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Udgivet i:Nucl Med Biol
Main Authors: Plotnik, David A., Wu, Stephen, Linn, Geoffrey R., Yip, Franco Chi Tat, Comandante, Natacha Lou, Krohn, Kenneth A, Toyohara, Jun, Schwartz, Jeffrey L.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4387014/
https://ncbi.nlm.nih.gov/pubmed/25659855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nucmedbio.2014.12.005
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