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Signalling pathways and mechanisms of protection in pre- and postconditioning: historical perspective and lessons for the future

Ischaemic pre- and postconditioning are potent cardioprotective interventions that spare ischaemic myocardium and decrease infarct size after periods of myocardial ischaemia/reperfusion. They are dependent on complex signalling pathways involving ligands released from ischaemic myocardium, G-protein...

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Détails bibliographiques
Publié dans:Br J Pharmacol
Auteurs principaux: Cohen, Michael V, Downey, James M
Format: Artigo
Langue:Inglês
Publié: BlackWell Publishing Ltd 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4386972/
https://ncbi.nlm.nih.gov/pubmed/25205071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12903
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