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A pharmacokinetic and pharmacodynamic comparison of a novel pegylated recombinant consensus interferon-α variant with peginterferon-α-2a in healthy subjects

AIMS: The aims of the study were to assess the pharmacokinetics, pharmacodynamics, safety and tolerability of a novel, pegylated recombinant human consensus interferon-α variant (PEG-IFN-SA) in healthy volunteers. A pharmacokinetic and pharmacodynamic comparison of PEG-IFN-SA and peginterferon-α-2a...

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Publicado en:Br J Clin Pharmacol
Main Authors: Zheng, Li, Li, Mao Ping, Gou, Zhong Ping, Wang, Ying, Xu, Nan, Cai, Yong Ming, Luo, Hua
Formato: Artigo
Idioma:Inglês
Publicado: Blackwell Science Inc 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4386949/
https://ncbi.nlm.nih.gov/pubmed/25297637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12528
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