Artemether-lumefantrine co-administration with antiretrovirals: population pharmacokinetics and dosing implications

AIM: Drug–drug interactions between antimalarial and antiretroviral drugs may influence antimalarial treatment outcomes. The aim of this study was to investigate the potential drug–drug interactions between the antimalarial drugs, lumefantrine, artemether and their respective metabolites desbutyl-lu...

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Dettagli Bibliografici
Pubblicato in:Br J Clin Pharmacol
Autori principali: Hoglund, Richard M, Byakika-Kibwika, Pauline, Lamorde, Mohammed, Merry, Concepta, Ashton, Michael, Hanpithakpong, Warunee, Day, Nicholas P J, White, Nicholas J, Äbelö, Angela, Tarning, Joel
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Science Inc 2015
Soggetti:
Pharmacokinetics
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4386948/
https://ncbi.nlm.nih.gov/pubmed/25297720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12529
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