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Dose-Dependent Effects of Morphine Exposure on mRNA and microRNA (miR) Expression in Hippocampus of Stressed Neonatal Mice

Morphine is used to sedate critically ill infants to treat painful or stressful conditions associated with intensive care. Whether neonatal morphine exposure affects microRNA (miR) expression and thereby alters mRNA regulation is unknown. We tested the hypothesis that repeated morphine treatment in...

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Vydáno v:PLoS One
Hlavní autoři: McAdams, Ryan M., McPherson, Ronald J., Beyer, Richard P., Bammler, Theo K., Farin, Frederico M., Juul, Sandra E.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4386824/
https://ncbi.nlm.nih.gov/pubmed/25844808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0123047
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