GEM-loaded magnetic albumin nanospheres modified with cetuximab for simultaneous targeting, magnetic resonance imaging, and double-targeted thermochemotherapy of pancreatic cancer cells

BACKGROUND: Targeted delivery is a promising strategy to improve the diagnostic imaging and therapeutic effect of cancers. In this paper, novel cetuximab (C225)-conjugated, gemcitabine (GEM)-containing magnetic albumin nanospheres (C225-GEM/MANs) were fabricated and applied as a theranostic nanocarr...

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Vydáno v:Int J Nanomedicine
Hlavní autoři: Wang, Ling, An, Yanli, Yuan, Chenyan, Zhang, Hao, Liang, Chen, Ding, Fengan, Gao, Qi, Zhang, Dongsheng
Médium: Artigo
Jazyk:Inglês
Vydáno: Dove Medical Press 2015
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Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4386779/
https://ncbi.nlm.nih.gov/pubmed/25848268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S77642
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