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Mediator Can Regulate Mitotic Entry and Direct Periodic Transcription in Fission Yeast

Cdk8 is required for correct timing of mitotic progression in fission yeast. How the activity of Cdk8 is regulated is unclear, since the kinase is not activated by T-loop phosphorylation and its partner, CycC, does not oscillate. Cdk8 is, however, a component of the multiprotein Mediator complex, a...

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Détails bibliographiques
Publié dans:Mol Cell Biol
Auteurs principaux: Banyai, Gabor, Lopez, Marcela Davila, Szilagyi, Zsolt, Gustafsson, Claes M.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4386457/
https://ncbi.nlm.nih.gov/pubmed/25154415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00819-14
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