Universal pathway for posttransfer editing reactions: Insights from the crystal structure of TtPheRS with puromycin

At the amino acid binding and recognition step, phenylalanyl-tRNA synthetase (PheRS) faces the challenge of discrimination between cognate phenylalanine and closely similar noncognate tyrosine. Resampling of Tyr-tRNA(Phe) to PheRS increasing the number of correctly charged tRNA molecules has recentl...

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Detaylı Bibliyografya
Yayımlandı:Proc Natl Acad Sci U S A
Asıl Yazarlar: Tworowski, Dmitry, Klipcan, Liron, Peretz, Moshe, Moor, Nina, Safro, Mark G.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2015
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4386372/
https://ncbi.nlm.nih.gov/pubmed/25775602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1414852112
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