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Spatial proximity of homologous alleles and long noncoding RNAs regulate a switch in allelic gene expression

Physiological processes rely on the regulation of total mRNA levels in a cell. In diploid organisms, the transcriptional activation of one or both alleles of a gene may involve trans-allelic interactions that provide a tight spatial and temporal level of gene expression regulation. The mechanisms un...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Stratigi, Kalliopi, Kapsetaki, Manouela, Aivaliotis, Michalis, Town, Terrence, Flavell, Richard A., Spilianakis, Charalampos G.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4386343/
https://ncbi.nlm.nih.gov/pubmed/25770217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1502182112
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