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TALE nickase-mediated SP110 knockin endows cattle with increased resistance to tuberculosis
Transcription activator-like effector nuclease (TALEN)-mediated genome modification has been applied successfully to create transgenic animals in various species, such as mouse, pig, and even monkey. However, transgenic cattle with gene knockin have yet to be created using TALENs. Here, we report si...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4386332/ https://ncbi.nlm.nih.gov/pubmed/25733846 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1421587112 |
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