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Nucleotide exchange in dimeric MCAK induces longitudinal and lateral stress at microtubule ends to support depolymerization
Members of the kinesin-13 sub-family use their motor domains in an unconventional fashion to initiate microtubule depolymerization at microtubule (MT) ends, suggesting unique conformational transitions for lattice engagement, end adaptation or both. Using hydrogen/deuterium exchange and electron mic...
Guardat en:
| Publicat a: | Structure |
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| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4386277/ https://ncbi.nlm.nih.gov/pubmed/25066134 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2014.06.010 |
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