MicroRNA-500 sustains nuclear factor-κB activation and induces gastric cancer cell proliferation and resistance to apoptosis

Ubiquitin deconjugation of key signalling molecules by deubiquitinases (DUBs) such as cylindromatosis (CYLD), A20, and OTU deubiquitinase 7B (OTUD7B) has emerged as an important regulatory mechanism in the downregulation of NF-κB signalling and homeostasis. However, how these serial negative regulat...

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Pubblicato in:Oncotarget
Autori principali: Zhang, Liang, Ding, Ya, Yuan, Zhongyu, Liu, Junling, Sun, Jian, Lei, Fangyong, Wu, Shu, Li, Su, Zhang, Dongsheng
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2015
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4385865/
https://ncbi.nlm.nih.gov/pubmed/25595906
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