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Immunohistochemical quantification of the cobalamin transport protein, cell surface receptor and Ki-67 in naturally occurring canine and feline malignant tumors and in adjacent normal tissues

Cancer cells have an obligate need for cobalamin (vitamin B(12)) to enable DNA synthesis necessary for cellular replication. This study quantified the immunohistochemical expression of the cobalamin transport protein (transcobalamin II; TCII), cell surface receptor (transcobalamin II-R; TCII-R) and...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Sysel, Annette M., Valli, Victor E., Bauer, Joseph A.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4385855/
https://ncbi.nlm.nih.gov/pubmed/25633912
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