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Enantioselective Desymmetrization via Carbonyl-Directed Catalytic Asymmetric Hydroboration and Suzuki-Miyaura Cross-Coupling

[Image: see text] The rhodium-catalyzed enantioselective desymmetrization of symmetric γ,δ–unsaturated amides via carbonyl-directed catalytic asymmetric hydroboration (directed CAHB) affords chiral secondary organoboronates with up to 98% ee. The chiral γ–borylated products undergo palladium-catalyz...

詳細記述

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書誌詳細
出版年:Org Lett
主要な著者: Hoang, Gia L., Yang, Zhao-Di, Smith, Sean M., Pal, Rhitankar, Miska, Judy L., Pérez, Damaris E., Pelter, Libbie S. W., Zeng, Xiao Cheng, Takacs, James M.
フォーマット: Artigo
言語:Inglês
出版事項: 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4385711/
https://ncbi.nlm.nih.gov/pubmed/25642639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol503764d
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