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The combinatorial synthesis and chemical and biological evaluation of a 1,4-benzodiazepine library.

A library of 192 structurally diverse 1,4-benzodiazepine derivatives containing a variety of chemical functionalities including amides, carboxylic acids, amines, phenols, and indoles was constructed from three components, 2-aminobenzophenones, amino acids, and alkylating agents, by employing Geysen&...

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Detalhes bibliográficos
Main Authors: Bunin, B A, Plunkett, M J, Ellman, J A
Formato: Artigo
Idioma:Inglês
Publicado em: 1994
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC43857/
https://ncbi.nlm.nih.gov/pubmed/8197123
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